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EU-TIRADS SCORE

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The EU TIRADS score Acronym for: European Thyroid Imaging-Reporting and Data System: is a method implemented by the European Thyroid Association in 2017.

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The objective of allowing reproducible analysis of thyroid nodules on ultrasound thus allowing   better monitoring and better management of patients with thyroid pathology.

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The EU TIRADS score is based on two elements: the cardinal signs and the accessory signs.

  1. Cardinal signs: the presence of a cardinal sign  places the nodule in the group  EU TIRADS 5  (according to the number of signs_ cardinals the risk varies between 26 and 87%).

  2. Accessory signs: in the absence of cardinal signs, echogenicity will determine the EU TIRADS 4, 3 and 2 score.

 

Accessory signs  will modulate the risk within each group (cancer risk of 17 – 0%).

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This EU-TIRADS system includes:

  1. A lexicon containing key descriptive words, illustrated with an atlas (“typical” images)

  2. A score for malignancy risk stratification ranging from 1 to 5

  3. A standardized report with diagram

  4. Support recommendations

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The EU TIRADS score is based on cardinal signs and accessory signs.

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The cardinal signs will classify the nodule in a category and the accessory signs will modulate the risk  within each category.

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The cardinal signs

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  • The EU TIRADS 5 score

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The cardinal signs of thyroid cancer are four in number:

  1. The shape of the nodule: not oval, thicker than wide and/or wide.

  2. The irregular contours of the nodule: spiculated or lobulated.

  3. The echogenicity of the nodule: marked hypoechogenicity.

  4. The microcalcifications.

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The presence of one of the cardinal signs places the nodule in category 5.

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The non-oval nodule shape

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The non-oval shape is a suspicious sign  so the nodule is classified EU TIRADS  5.

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Oval shape

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Oval shape

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Non-oval shape

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Non-oval shape

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The irregular contours of the nodule: spicules or lobules

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It takes at least three spiculations or three  lobulations.

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Regular contours

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Lobulated contours

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Spiculated contours

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Lobulated contours

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The strong hypoechogenicity

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Strong hypoechogenicity

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Strong hypoechogenicity

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The strong hypoechogenicity of the nodule is a cardinal sign and the hypoechogenicity must be compared to the superficial muscle and not to the healthy thyroid parenchyma.

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Microcalcifications

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Hyperechoic, rounded or rarely linear pits measuring less than 1 mm in diameter without shadow cone or comet-tail artifact.

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It is necessary to take into account their number and their grouping (at least 5).

Do not confuse the microcalcifications with the coloid type images at the level of the nodules.

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Microcalcifications

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Do not confuse microcalcifications and linear hyperechoic punctuations which have a comet-tail artefact, corresponding to the presence of intra-nodular colloid.

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image 3.jpg

peripheral microcalcifications      Documents Dr Laila Daibes Rachid ( colegio Brasileiro de radiologia

image 2.jpg

peripheral microcalcifications      Documents Dr Laila Daibes Rachid ( colegio Brasileiro de radiologia

Macrocalcifications are not specific to malignancy and their presence must be related to the other ultrasound signs present.

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The presence of cardinal signs at the level of a nodule means a very high risk of cancer which varies according to the number of signs present between 26% and 87%.

Beware of the fake EU TIRADS 5 score.

It is a highly hypoechoic nodule without any internal vascularization and this aspect is the consequence of the complete resorption of the intra-nodular haemorrhagic liquid component.

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False EU-TIRADS 5 score (nodulehemorrhagic with a resorption complete fluid component)

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False EU-TIRADS 5 score (nodulehemorrhagic with a resorption complete fluid component)

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Accessory signs

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Some accessory signs increase the risk of cancer and others decrease the risk.

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These signs participate in the modulation of the risk within each EU-TIRADS score without modifying it.

 

Accessory signs that increase the risk are:​

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Discontinuous peripheral macrocalcifications

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Pathological elastography

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Round shape

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Central vascularization

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Non-parallel orientation

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 Extra capsular extension

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Accessory signs that decrease the risk of malignancy are:

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Fine and complete halo

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Normal elastography

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Peripheral vascularization

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Mixed echostructure

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colloidal granulation

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flattened shape

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The vascularization

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Controversial value in the literature, vascularization is not retained in the EU TIRADS system.

The  vascularization provides few  diagnostic arguments, however in isoechoic solid nodules > 20 mm with strong central vascularization, the risk of follicular cancer increases, on the other hand a peripheral vasculature decreases the risk.

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Cancerfollicular with strong peripheral and central vascularization

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  • The EU TIRADS 4 score

 

Moderately hypoechoic nodule compared to the superficial muscle.

Theoretical risk  6-17%.

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  • The EU TIRADS 3 score

 

Hyperechoic or isoechoic nodule.

Theoretical risk 2-4%.

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  • The EU TIRADS 2 score

 

Cystic nodule colloidal type or a spongiform type nodule.

Theoretical risk 0%.

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The standardized report must include a description of the nodule in 10 points with a diagram.

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The standardized report must include a course of action for management.

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Multinodular thyroids with the EU TIRADS score.

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The strategy consists of:

  1. Look for high-risk nodules first (EU TIRADS5).

  2. Look for nodules at intermediate risk (EU TIRADS 4) and describe nodules > 5 mm.

  3. Look for low-risk nodules (EU TIRADS 3) and describe nodules > 10 mm.


The EU TIRADS score is based on echogenicity.

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© 2021

Content written by Dr. Haitham SHARARA.

Site created by Christophe NOËL

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